重组人生长激素（HGH）技术转让

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英 文 名：
Recombinant Human Growth Hormone (rHGH)
英文缩写：
HGH、rhHGH、rhuHGH、rh-HGH、rhu-HGH、Human Growth Hormone
中 文 名：
重组人表皮细胞生长因子，重组人表皮生长因子，表皮生长因子，人表皮生长因子
来    源：
毕赤酵母（真核细胞）
描    述：
重组人生长激素（HGH）由191个氨基酸组成的相对分子量为22.125kD的单链肽类激素。采用基因工程技术和独特的色谱技术分离纯化、冻干制备。HGH具有多种生物活性。
品质:
外观：白色疏松状冻干粉。
纯度：>95% ，采用反相-高效液相（RP-HPLC）方法测定。
纯度：>95% ，采用还原型聚丙烯酰胺凝胶电泳（SDS-PAGE），银染检测。
生物活性：3 IU/mg.
PH值：7.2
包装:
0.1mg、1mg、2 mg、10mg/西林瓶，粉状冻干品密封包装。
储存:
HGH冻干粉在室温下可存放180天；建议在2-8℃的冷柜中避光、密封保存，三年其生物活性不改变。
用途:
基因重组人生长激素与天然人生长激素一样，进入体内能通过肝生长调节素(生长素介质)及组织多肽生长因子的作用，促进骨、软骨生长，增加蛋白质合成。纠正手术等创伤后的负氮平衡状态，纠正重度感染及肝硬化等所致的低蛋白血症；刺激免疫球蛋白合成，刺激淋巴样组织、巨噬细胞和淋巴细胞的增殖，增强抗感染能力；刺激烧伤创面及手术切口胶原体细胞合成纤维细胞，巨噬细胞分裂增殖，加速伤口愈合；促进心肌蛋白合成，增加心肌收缩力，降低心肌耗氧量；调节脂肪代谢，降低血清胆固醇、低密度脂蛋白的水平；补充生长激素不足或缺乏，调节成人的脂肪代谢、骨代谢、心肾功能等。

应用范围:
美容：
(1)注射使用：
通过注射重组人生长激素可以使皮肤增加弹性，能使浑身肌肉变紧，皱纹消失，皮肤异常年轻细嫩，绝无副作用，是目前最好的美容产品。同时可促进脂肪消耗，减轻肥胖，改善体能，提高记忆力。
(2)外用：
将生长激素添加在抗衰老、嫩肤、减肥等化妆品中，作为添加剂使用，可以使美容产品效果明显，起到快速美容、嫩肤、减肥、除皱等特殊功效。
医药：
生长激素在临床上主要用于垂体性侏儒症（即用于增高）、成人生长激素缺乏症、慢性充血性心衰、
预防心梗后室壁瘤和心肌缺血再灌注损伤、慢性阻塞性肺气肿病人、心肺移植及肺移植病人、慢性肝脏疾病、急性坏死性胰腺炎、慢性肾病患者、烧伤、外伤、大手术、严重感染等。
生化试剂：
本品可为生化试剂在科研、检测等多个领域中使用。


Recombinant Human Growth Hormone (rHGH)

Name:
Recombinant Human Growth Hormone (rHGH)
Synonyms:
HGH、rhHGH、rhuHGH、rh-HGH、rhu-HGH、Human Growth Hormone
Description:
Human growth hormone is a single chain peptide hormone formed by 191 amino acids and molecular weight is 22125 Dalton. The HGH is purified by gene techniques and proprietary chromatographic techniques. HGH has a wide range of biological activity.
Source:
P.pastoris
Physical Appearance:
White lyophilized（freeze-dried）powder
Purity:
Greater than 95% as determined by:
(a)        Analysis by RP-HPLC.
(b)        Analysis by SDS-PAGE.
Amino acid sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Phe-Pro-Thr-Ile, which agrees with the sequence of native human HGH.
Biological Activity:
ProSpec’s GH is contains 3 units/mg.
Packing:
In Penicillin vial, inner sealed with 0.1mg,、1mg、2mg、10mgfreeze-dried power.
Storage:
Lyophilized Epidermal Growth Factor although stable at room temperature for 18 days; and stored at 2-8°C for 3 years.
Usage:
Gene recombinant human growth hormone is the same as natural human growth hormone. HGH can promote bone and cartilage growthas well as increase protein synthesis through liver somatomedin and tissue polypeptide growth factor.correct the post-traumatic state of negative nitrogen as well as hypoproteinemia induced by severe infection and cirrhosis; stimulate immunoglobulin synthesis, stimulate the proliferation of lymphoid tissue, macrophages and lymphocyte, and enhance the capacity of anti-infective ;stimulate burn wound and operative incision collagenous soma to synthesize fiber cell, macrophages proliferation,accelerate wound healing; promote myocardial protein synthesis, increase myocardial contractility and reduce myocardial oxygen consumption; regulating fat metabolism, reducing serum cholesterol, low - density lipoprotein level;supplyment hormone deficiencies or lack, regulatadult fat metabolism, bone metabolism, heart and kidney functions.
Application scope:
Cosmetology:
(1) injection use:
Injection of recombinant human growth hormone can make the skin more flexible, can change all the muscles tight and wrinkles disappear, delicate young skin with no side effects.It is the best beauty products so far. At the same time it can promote fat consumption, obesity reduction, physical and memory improvement.
(2)external use:
As the additives,HGH having the effect of anti-aging, rejuvenation and weight reduction can be added to cosmetics,which makes beauty products effect obvious,having a special effects in quick beauty, skin rejuvenation, lose weight,wrinkles elimination.
medicine:
HGH is mainly used in clinical pituitary dwarfism (ie for higher), adult growth hormone deficiency, chronic congestive heart failure,preventing ventricular aneurysm after myocardial infarctionand myocardial ischemia-reperfusion injury, chronic obstructive pulmonary emphysema patients, heart and lung transplants and lung transplant patients, chronic liver disease, acute necrotizing pancreatitis, chronic kidney disease, burns, trauma, large surgery, severe infection
Biochemical reagent:
This product can be used as biochemical reagent in research, detection and many other various fields.